Collaborative Research Center/Transregio 63

"Integrated Chemical Processes in Liquid Multiphase Systems"

>Research>Project Area B>Project B1

B1 Optimal Reactor Design and Operation for Liquid Multiphase Systems

Sub-Coordinators: Prof. Dr.-Ing. Kai Sundmacher, Dr.-Ing. Katharina Zähringer
Researchers: M. Sc. Karsten Rätze, M. Sc. Péter Kováts

 

Subproject B1 is involved in the synthesis of new and innovative reaction networks. Based on the elementary process functions (EPF) methodology developed during the previous funding periods, the design approach is generalized to consider:

  • complex reaction networks with multiple reaction steps,
  • a variety of phase combinations (gas/liquid, liquid/liquid, gas/liquid/liquid),
  • different solvent systems.

By using dynamic optimization and optimal control, the optimal operating conditions can be derived for different objectives. Evaluation of the control profiles allows for the derivation of reactor-separator-networks and integrated reactor-separator-systems which can be used for the development of integrated processes together with subproject D1. In B1 the approach is exemplified using the reductive amination of 1-undecanal and the hydroaminomethylation of 1-decene.

 

Besides the process design, innovative reactor modules are build and characterized experimentally as well as numerically to quantify the effects of

on the stability and robustness of the reactor. Special attention is also given to the mixing properties in the case of different phase combinations. These investigations are performed using stand-alone models and under mini-plant conditions together with the subprojects D2 and D3 to validate the methodological approach and to further improve the reactor design.

 

More information:

 

Connected projects within the Collaborative Research Center/Transregio 63

A2 (Schomäcker): Catalytic Upgrading of Long Chain Olefins by Hydroformylation and Hydroesterification in Surfactant Modified Multi Phase Systems

A3 (Hamel, Seidel-Morgenstern): Kinetics of reductive amination and hydroaminomethylation in reactive multiphase fluid systems

A4 (Sadowski, Stein): Choice of solvent for selective control of kinetics and thermodynamics of chemical reactions

A10 (Böhm, Hecht, Kraume): Gas/Liquid Mass Transfer in Reactive Multiphase Systems

A11 (Seidensticker, Vogt): Homogeneously catalyzed reductive amination of long-chain aldehydes and hydroaminomethylation of long-chain alkenes with integrated catalyst separation in thermoregulated phase systems

B8 (Kraume, Thévenin): Characterization, modeling and simulation of phase separation in micellar multiphase systems

B9 (Kienle, Sundmacher): Integrated design of thermomorphic multicomponent systems (TMS) and separation processes for the efficient recovery of homogeneous catalysts and solvents

D1 (Engell, Sadowski, Sundmacher): Fast model-based design of chemical processes with several liquid phases

D2 (Repke): Demonstration of the Fast Track Process Development and of the Optimal Operation of the Reductive Amination of Long-chained Aldehydes in Emulsion Systems

D3 (Skiborowski, Vogt): Development and testing of integrated reaction and catalyst separation for the homogenously catalyzed reductive amination and hydroaminomethylation of long chain alkenes in a miniplant

 

Recent Publications

Jokiel, M.; Rätze, K. H. G.; Kaiser, N. M.; Künnemann, K.; Hollenbeck, J. P.; Dreimann, Dreimann J.M., Vogt D. and Sundmacher K.  Miniplant scale evaluation of a semibatch-continuous tandem reactor system for the hydroformylation of long-chain olefins. Ind. Eng. Chem. Res., 58,7, 2471-2480, 2019. [DOI: 10.1021/acs.iecr.8b03874]

Khot, P., Mansour, M., Thévenin, D., Nigam, K. D. P. and Zähringer, K.: Improving the mixing characteristics of coiled configurations by early flow inversion, Chemical Engineering Research and Design, 146, 324-335, 2019, [doi.org/10.1016/j.cherd.2019.04.016]

Mansour, M., Thévenin, D., Nigam, K. D. P. and Zähringer, K. Generally-valid optimal Reynolds and Dean numbers for efficient liquid-liquid mixing in helical pipes., Chem. Eng. Sci., 201, 382-385, 2019. [doi.org/10.1016/j.ces.2019.03.003]


Aydin, E.; Dominique, B.; Sundmacher, K. NMPC using Pontryagin’s Minimum Principle-Application to a two-phase semi-batch hydroformylation reactor under uncertainty. Com. Chem. Eng., 108, 47-56, 2018. [doi.org/10.1016/j.compchemeng.2017.08.010]

Aydin, E.; Dominique, B.; Sundmacher, K. Computationally efficient NMPC for batch and semi-batch processes using parsimonious input parameterization. Jour. Proc. Eng., 66, 12-22, 2018. [doi.org/10.1016/j.jprocont.2018.02.012]

Jokiel M.; Sundmacher K. Spezielle labortechnische Reaktoren: Wendelrohrreaktor. In: Reschetilowski W. (eds) Handbuch Chemische Reaktoren. Springer Reference Naturwissenschaften.Springer Spektrum, Berlin, Heidelberg. 2018. DOI: https://doi.org/10.1007/978-3-662-56444-8_46-1

Jokiel, M.; Kaiser, N. M.; Kováts, P.; Mansour, M.; Zähringer, K.; Nigam, K. D.P.; Sundmacher, K. Helically coiled segmented flow tubular reactor for the hydroformylation of long-chain olefins in a thermomorphic multiphase system. Chemical Engineering Journal, in press, 2018. [doi.org/10.1016/j.cej.2018.09.221]

Kaiser, N. M.; Flassig, R. J.; Sundmacher, K. Reactor-network synthesis via flux profile analysis. Chem. Eng. Jour., 335, 1018-1030, 2018. [doi.org/10.1016/j.cej.2017.09.051]

Kováts, P.; Pohl, D.; Thévenin, D.; Zähringer, K. Optical determination of oxygen mass transfer in a helically-coiled pipe compared to a straight horizontal tube. Chemical Engineering Science., 190, 237-285, 2018. [doi.org/10.1016/j.ces.2018.06.029]

Mansour, M.; Janiga, G.; Nigam, K.D.P.; Thevenin, D.; Zahringer, K. Numerical Study of heart transfer and thermal homogenization in a helical reactor. Chem. Eng., 177, 369-379, 2018. [doi.org/10.1016/j.ces.2017.11.031]

Mansour, M.; Khot, P.; Thévenin, D.; Nigam, K. D. P.; Zähringer, K. Optimal Reynolds number for liquid-liquid mixing in helical pipes. Chemical Engineering Science, in press, 2018. [doi.org/10.1016/j.ces.2018.09.046]

Rätze, K. H. G.; Jokiel, M.; Kaiser, N. M.; Sundmacher, K. Cyclic Operation of a Semi-Batch Reactor for the Hydroformylation of Long-Chain Olefins and Integration in a Continuous Production Process. Chemical Engineering Journal, in press, 2018. [doi.org/10.1016/j.cej.2018.11.151]

Zähringer, K.; Wagner, L.-M.; Thévenin, D.; Siegmund, P.; Sundmacher, K. Particle-image-velocimetry measurements in organic liquid multiphase systems for an optimal reactor design and operation. J. Visualization, 21(1), 5-17, 2018. [doi:10.1007/s12650-017-0435-5]


Aydin, E.; Bonvin, D.; Sundmacher, K. Dynamic optimization of constrained semi-batch processes using Pontryagin's minimum principle - An effective quasi-Newton approach. Comp. Chem. Eng., 99, 135-144, 2017. [doi.org/10.1016/j.compchemeng.2017.01.019]

Jokiel, M.; Wagner, L.-M.; Mansour, M.; Kaiser, N. M.; Zähringer, K.; Janiga, G.; Nigam, K. D. P.; Thévenin, D.; Sundmacher, K. Measurement and simulation of mass transfer and backmixing behavior in a gas-liquid helically coiled tubular reactor. Chem. Eng. Sci., 170, 410-421, 2017. [doi: https://doi.org/10.1016/j.ces.2017.01.027]

Kaiser, N.M., Jokiel, M., McBride, K.,  Flassig, R.J., Sundmacher, K. Optimal reactor design via Flux Profile Analysis for an Integrated Hydroformylation Process Using a Thermomorphic Solvent Systems for Catalyst Recovery. Ind. Eng. Chem. Res. 56, 11507-11518, 2017. [DOI:10.1021/acs.iecr.7b01939]

Mansour, M.; Liu, Z.; Janiga, G.; Nigam, K. D. P.; Sundmacher, K.; Thévenin, D.; Zähringer, K. Numerical study of liquid-liquid mixing in helical pipes. Chem. Eng. Sci., 172, 250-261, 2017. [doi: https://doi.org/10.1016/j.ces.2017.06.015]

Zähringer, K.; Wagner, L.-M.; Thévenin, D.; Siegmund, P.; Sundmacher, K. Particle-image-velocimetry measurements in organic liquid multiphase systems for an optimal reactor design and operation. J. Visualization, 1-13, 2017. [doi:10.1007/s12650-017-0435-5]

Zhou, T.; Zhou, Y.; Sundmacher, K. A hybrid stochastic–deterministic optimization approach for integrated solvent and process design. Chem. Eng. Sci., 159, 207-216, 2017. [doi: http://dx.doi.org/10.1016/j.ces.2016.03.011]


Kaiser, M. N.; Flassig, J. R.; Sundmacher, K. Design and Comparison of Optimal Reactor Concepts for the Hydroformylation of Olefins by Use of a Probabilistic Design Framework. 26th European Symposium on Computer Aided Process Engineering. 1365-1370, 2016. [http://hdl.handle.net/11858/00-001M-0000-002B-0FC8-7]

Kaiser, M. N.; Flassig, J. R.; Sundmacher, K. Probabilistic reactor design in the framework of elementary process functions. Comp. Chem. Eng., 94, 45-59, 2016. [doi.org/10.1016/j.compchemeng.2016.06.008]

McBride, K.; Gaide, T.; Vorholt, A. J.; Behr, A.; Sundmacher, K. Thermomorphic solvent selection for homogeneous catalyst recovery based on COSMO-RS. Chem. Eng. Process., 99, 97-106, 2016. [doi:10.1016/j.cep.2015.07.004]

McBride, K.; Kaiser, N. M.; Sundmacher, K. Integrated reaction-extraction process for the hydroformylation of long-chain alkenes with a homogeneuous catalyst. Comput. Chem. Eng., 2016.
[http://dx.doi.org/10.1016/j.compchemeng.2016.11.019]

Zhou, T.; Zhou, Y.; Sundmacher, K. A hybrid stochastic–deterministic optimization approach for integrated solvent and process design. Chem. Eng. Sci., 99, 1-10, 2016. [doi.org/10.1016/j.ces.2016.03.011]


Hentschel, B.; Kiedorf, G.; Gerlach, M.; Hamel, C.; Seidel-Morgenstern, A.; Freund, H.; Sundmacher, K. Model-Based Identification and Experimental Validation of the Optimal Reaction Route for the Hydroformylation of 1-Dodecene. Ind. Eng. Chem. Res., 54(6), 1755-1765, 2015. [doi:10.1021/ie504388t]

McBride, K.; Sundmacher, K. Data Driven Conceptual Process Design for the Hydroformylation of 1-Dodecene in a Thermomorphic Solvent System. Ind. Eng. Chem. Res., 54(26), 6761–6771, 2015. [doi:10.1021/acs.iecr.5b00795]

Zhou, T.; Lyu, Z.; Qi, Z.; Sundmacher, K. Robust design of optimal solvents for chemical reactions - A combined experimental and computational strategy. Chem. Eng. Sci., 137, 613-625, 2015. [doi:10.1016/j.ces.2015.07.010]

Zhou, T.; McBride, K.; Zhang, X.; Qi, Z.; Sundmacher, K. Integrated solvent and process design exemplified for a Diels-Alder reaction. AIChE J., 61(1), 147-158, 2015. [doi:10.1002/aic.14630]

Dissertations

Medeiros de Souza, L. G. Model optimization and techniques for the simulation of multiphase chemical reactors. Otto-von-Guericke-Universität Magdeburg, 2016. [More]


Peschel, A. Model-based design of optimal chemical reactors. Otto-von-Guericke-Universität Magdeburg, 2012.
[More]

Last updated:18-06-2019