Collaborative Research Center/Transregio 63
"Integrated Chemical Processes in Liquid Multiphase Systems"
Sub-Coordinator: Prof. Dr.-Ing. Jens-Uwe Repke
Researcher: M. Sc. Volodymyr Kozachynskyi
The hydroformylation of long alkenes in microemulsions has already been established in the past funding periods of InPROMPT. The applicability of the process concept with a highly selective homogeneously catalyzed reaction and a highly efficient catalyst recycling, using surfactant modified systems has yet to be transferred towards more complex reactions - like the reductive amination of long-chained aldehydes.
In D2 a fully automated mini-plant is used, to conduct experimental investigations on a continuous process for the reductive amination with rhodium catalysts in multiphase systems. To gain a deeper understanding of phenomena which occur during continuous long term operation and which were impossible to observe in a lab scale, the analytical instrumentation will be extended. Operating data will be used for model identification and validation of single units. This is done using an online adaptive Optimal Experimental Design and Parameter Estimation framework, which operates above the base control level of the mini-plant, keeping safety layers active. In doing so, the fast track process development for a new process with initially low knowledge on the process is to be demonstrated. Process control strategies for start-up and robust continuous operation will be implemented and tested. Following the concept of the modular plant design, alternative processes and apparatus designs will be installed, especially to tackle the separation of produced water from the reaction mixture and the overall challenging phase separation step.
A2 (Schomäcker): Influence of catalyst ligand complexes, network analysis of total and sub reaction networks, evaluation of catalyst deactivation
A9 (Enders, Sadowski): Solubilization of weakly polar compounds in micellar systems
A10 (Böhm, Hecht, Kraume): Gas/Liquid Mass Transfer in Reactive Multiphase Systems
B1 (Sundmacher, Zähringer): Exchange of kinetic data and models, validation of the optimal solvent system as well as dosing and temperature trajectories on reactor and process level
B6 (Drews, von Klitzing): Design of Pickering emulsions for the separation of products with different polarity
B8 (Kraume, Thévenin): Characterization, modeling and simulation of phase separation in micellar multiphase systems
D1 (Engell, Sadowski, Sundmacher): Fast model-based design of chemical processes with several liquid phases
D4 (Engell, Esche): Control and optimal operation of the reductive amination and of the hydroaminomethylation in the demonstration plants
Esche, E; Repke, J.U. Dynamic Process Operation Under Demand Response – A Review of Methods and Tools. Chem. Ing. Tech. 92, 12(898–1909) 2020. [DOI:doi.org/10.1002/cite.202000091]
Pogrzeba, T., Illner, M., Schmidt, M., Milojevic, N., Esche, E., Repke, J.-U., Schomäcker, R. Kinetics of Hydroformylation of 1‑Dodecene in Microemulsion Systems Using a Rhodium Sulfoxantphos Catalyst. Industrial & Engineering Chemistry Research, 58, 4443-4453, 2019, [doi.org/10.1021/acs.iecr.8b06157]
Illner, M.; Esche, E.; Repke, J.-U. Optimal Control of Surfactant containing Multiphase Systems - Challenges and Solution Strategies for a stable Mini-Plant Operation. Comput.-Aided Chem. Eng., 44, 739-744, 2018. [doi.org/10.1016/B978-0-444-64241-7.50118-X]
Misra, A.; Bonamy, C.; Medeiros de Souza, L.; Hohl, L.; Illner, M.; Kraume, M.; Repke, J.-U.; Thévenin, D. A multi-fluid approach to simulate separation of liquid-liquid systems in a gravity settler. Comput.-Aided Chem. Eng. 43, 31-36, 2018. [doi.org/10.1016/B978-0-444-64235-6.50008-5]